Genetic screens are a powerful tool to discover genes that are important in immune cell development and function.The evolutionarily conserved development of lymphoid cells paired with the genetic tractability of zebrafish make this a powerful model system for this purpose.We used a Tol2-based gene-breaking transposon to induce mutations in the zebr

Decarbonising and improving the energy efficiency of dwellings is a priority for climate and energy policy.However, integrated energy systems modelling, commonly used to inform decarbonisation pathways, typically does not capture the heterogeneity of the dwelling stock, particularly internal dwelling temperatures, a key determinant of the cost of s

Systemic juvenile idiopathic arthritis (sJIA) is the form of childhood arthritis whose treatment is most challenging.The demonstration of the prominent involvement of interleukin (IL)-1 in disease pathogenesis has provided the rationale for the Model Kits treatment with biologic medications that antagonize this cytokine.The three IL-1 blockers that

The relative importance of income earning potential versus consumptive values in setting ranchland prices is examined using a truncated hedonic model.The market value of New Mexico ranches is related to annual income earning potential Tops and other ranch characteristics including ranch size, location, elevation, terrain, and the amount of deeded,

To date, there is poor evidence on the transmission of infection in individuals handling the bodies of deceased persons infected with SARS-CoV-2 and in particular, during autopsies.The aim of this study was to demonstrate that when 6 Pin Wire Harness appropriate strategies are adopted autopsy is a safe procedure with a minimal infection risk for al